3 easy ways you can donate to support a worthy cause
Sickle Cell Foundation Nigeria
Bringing hope to the African child
Sickle cell disorder is by far the commonest inherited disorder in the world and three quarters of cases occur in Africa. In Nigeria, where it affects two out of every hundred children born, it causes suffering for innumerable patients and their families. However, despite its importance, until now there has been no dedicated sickle cell center in Africa. This is partly because the very scale of the problem makes it difficult to see how to start.
Sickle cell disorder is an inherited haemoglobin disorder comprising sickle cell anaemia (Hb SS) and some less prevalent but related conditions such as sickle haemoglobin C disorder (Hb SC) and sickle beta thalassaemia (Hb SBthal). The genes for these conditions arose by mutation but proliferated in areas where there is or there was a high incidence of falciparium malaria, the most lethal strain of malaria known to man.
Handbook on Management of Sickle Cell Disorder
Sickle cell disorder (SCD) is the commonest inherited disorder in tropical Africa and, Nigeria–the most populous African country–contributes about half of the estimated 300,000 newborns with SCD annually.
SCD occurs when an individual inherits the variant sickle haemoglobin (Hb S) from one parent and another variant Hb from the other parent. The latter variant Hb may also be an Hb S or may be a different variant Hb such as Hb C, Hb O-Arab, or reduced or absent production of the β-haemoglobin chain, etc.