Sickle cell disorder (SCD) is the commonest inherited disorder in tropical Africa and, Nigeria–the most populous African country–contributes about half of the estimated 300,000 newborns with SCD annually.
SCD occurs when an individual inherits the variant sickle haemoglobin (Hb S) from one parent and another variant Hb from the other parent. The latter variant Hb may also be an Hb S or may be a different variant Hb such as Hb C, Hb O-Arab, or reduced or absent production of the β-haemoglobin chain, etc.
DISCLAIMER: This handbook is exclusively for Doctors and Nurses.
If you wish to seek clarification on this material, please don’t hesitate to get in touch with The Sickle Cell Foundation.